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Article

The Akt signaling pathway is required for tissue maintenance and regeneration in planarians.

BMC developmental biology - 11 Apr 2016

Peiris T Harshani, Ramirez Daniel, Barghouth Paul G, Oviedo Néstor J

Abstract excerpt

BACKGROUND: Akt (PKB) is a serine threonine protein kinase downstream of the phosphoinositide 3-kinase (PI3K) pathway. In mammals, Akt is ubiquitously expressed and is associated with regulation of cellular proliferation, metabolism, cell growth and cell death. Akt has been widely studied for its central role in physiology and disease, in particular cancer where it has become an attractive pharmacological target....

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Identifiers

PMID: 27068018
DOI: 10.1186/s12861-016-0107-z
PMCID: PMC4827215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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