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Article

MnSOD and GPx1 polymorphism relationship with coronary heart disease risk and severity.

Biological research - 11 Apr 2016

Souiden Yosra, Mallouli Hela, Meskhi Salah, Chaabouni Yassine, Rebai Ahmed, Chéour Foued, Mahdouani Kacem

Abstract excerpt

BACKGROUND: Disturbance of the equilibrium between reactive oxygen species (ROS) and anti-oxidants (AOX) has been implicated in various diseases, including atherosclerosis, the most common pathologic process underlying coronary heart disease (CHD). Thus, the defense systems against ROS are critical protecting blood vessel walls against oxidative damage. In this study, we investigate whether Ala16Val MnSOD and...

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Identifiers

PMID: 27067415
DOI: 10.1186/s40659-016-0083-6
PMCID: PMC4828869

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