Article
FXYD5: Na+/K+-ATPase Regulator in Health and Disease
30 Mar 2016
Abstract excerpt
FXYD5 (Dysadherin, RIC) is a single span type I membrane protein that plays multiple roles in regulation of cellular functions. It is expressed in a variety of epithelial tissues and acts as an auxiliary subunit of the Na(+)/K(+)-ATPase. During the past decade, a correlation between enhanced expression of FXYD5 and tumor progression has been established for various tumor types. In this review, current knowledge...
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