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Article

DNA repair gene XPD Asp312Asn and XRCC4 G-1394T polymorphisms and the risk of autism spectrum disorder.

Cellular and molecular biology (Noisy-le-Grand, France) - 20 Mar 2016

Dasdemir S, Guven M, Pekkoc K C, Ulucan H, Dogangun B, Kirtas E, Kadak M T, Kucur M, Seven M

Abstract excerpt

Autism spectrum disorder (ASD) is a complex disorder, and its extreme heterogeneity further complicates our understanding of its biology. Epidemiological evidence from family and twin studies supports a strong genetic component in ASD etiology. Oxidative stress and abnormal DNA methylation have been implicated in the pathophysiology of ASD. Brain tissues from ASD cases showed higher levels of oxidative stress...

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PMID: 27064873

Genes

XRCC4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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