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Carbapenem Resistance Mechanisms in Pseudomonas aeruginosa Clinical Isolates

1 Feb 2001

Abstract excerpt

In order to define the contributions of the mechanisms for carbapenem resistance in clinical strains of Pseudomonas aeruginosa, we investigated the presence of OprD, the expressions of the MexAB-OprM and MexEF-OprN systems, and the production of the beta-lactamases for 44 clinical strains. All of the carbapenem-resistant isolates showed the loss of or decreased levels of OprD. Three strains overexpressed the...

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Identifiers

PMID: 11158744
DOI: 10.1128/aac.45.2.480-484.2001

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