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Article

LRBA deficiency with autoimmunity and early onset chronic erosive polyarthritis.

Clinical immunology (Orlando, Fla.) - 1 Jul 2016

Lévy Eva, Stolzenberg Marie-Claude, Bruneau Julie, Breton Sylvain, Neven Bénédicte, Sauvion Sylvie, Zarhrate Mohammed, Nitschké Patrick, Fischer Alain, Magérus-Chatinet Aude, Quartier Pierre, Rieux-Laucat Frédéric

Abstract excerpt

LRBA (lipopolysaccharide-responsive and beige-like anchor protein) deficiency associates immune deficiency, lymphoproliferation, and various organ-specific autoimmunity. To date, prevalent symptoms are autoimmune cytopenias and enteropathy, and lymphocytic interstitial lung disease. In 2 siblings from a consanguineous family presenting with early onset polyautoimmunity, we presumed autosomal recessive inheritance...

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Source

Identifiers

PMID: 27057999
DOI: 10.1016/j.clim.2016.03.006

Genes

LRBA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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