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Article

Atypical manifestation of LRBA deficiency with predominant IBD-like phenotype.

Inflammatory bowel diseases - 1 Jan 2015

Serwas Nina Kathrin, Kansu Aydan, Santos-Valente Elisangela, Kuloğlu Zarife, Demir Arzu, Yaman Aytaç, Gamez Diaz Laura Yaneth, Artan Reha, Sayar Ersin, Ensari Arzu, Grimbacher Bodo, Boztug Kaan

Abstract excerpt

BACKGROUND: Inflammatory bowel diseases (IBDs) denote a heterogeneous group of disorders associated with an imbalance of gut microbiome and the immune system. Importance of the immune system in the gut is endorsed by the presence of IBD-like symptoms in several primary immunodeficiencies. A fraction of early-onset IBDs presenting with more severe disease course and incomplete response to conventional treatment is...

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Source

Identifiers

PMID: 25479458
DOI: 10.1097/MIB.0000000000000266

Genes

LRBA

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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