Factors influencing the effect size distribution of adaptive substitutions.

Abstract excerpt

The distribution of effect sizes of adaptive substitutions has been central to evolutionary biology since the modern synthesis. Early theory proposed that because large-effect mutations have negative pleiotropic consequences, only small-effect mutations contribute to adaptation. More recent theory suggested instead that large-effect mutations could be favoured when populations are far from their adaptive peak....

Topics

• Adaptation, Biological
• Animals
• Biological Evolution
• Models, Biological
• Mutation
• Plants