Article
Interleukin-19 induces angiogenesis in the absence of hypoxia by direct and indirect immune mechanisms.
American journal of physiology. Cell physiology - 1 Jun 2016
Kako Farah, Gabunia Khatuna, Ray Mitali, Kelemen Sheri E, England Ross N, Kako Bashar, Scalia Rosario G, Autieri Michael V
Abstract excerpt
Neovascularization and inflammation are independent biological processes but are linked in response to injury. The role of inflammation-dampening cytokines in the regulation of angiogenesis remains to be clarified. The purpose of this work was to test the hypothesis that IL-19 can induce angiogenesis in the absence of tissue hypoxia and to identify potential mechanisms. Using the aortic ring model of...
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