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Article

Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF

6 Apr 2016

Abstract excerpt

STUDY QUESTION: Are significant abnormalities in outward (K(+)) conductance and resting membrane potential (Vm) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success? SUMMARY ANSWER: Negligible outward conductance (≈5% of patients) or an enhanced inward conductance (≈4% of patients), both of which caused depolarization of Vm, were...

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PMID: 27052499
DOI: 10.1093/humrep/dew056

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