Article
Azole susceptibility in clinical and environmental isolates of Aspergillus fumigatus from eastern Hokkaido, Japan.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Sept 2016
Toyotome Takahito, Fujiwara Takayuki, Kida Hideyuki, Matsumoto Munehiro, Wada Terumi, Komatsu Ryoichi
Abstract excerpt
Azole antifungals are used not only clinically for fungal infections but also used as agricultural fungicides. Recently, azole-resistant Aspergillus fumigatus containing a tandem repeat in the promoter region of cyp51A combined with amino acid substitution(s) appears in the environment in Eurasia, especially in several European countries. Although azole fungicides have been used in Japan, especially in Hokkaido,...
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