Article
Metabolically defined body size and body shape phenotypes and risk of postmenopausal breast cancer in the European Prospective Investigation into Cancer and Nutrition.
Cancer medicine - 1 Jun 2023
Mahamat-Saleh Y, Rinaldi S, Kaaks R, Biessy C, Gonzalez-Gil E M, Murphy N, Le Cornet C, Huerta J M, Sieri S, Tjønneland A, Mellemkjaer L, Guevara M, Overvad K, Perez-Cornago A, Tin Tin S, Padroni L, Simeon V, Masala G, May A, Monninkhof E, Christakoudi S, Heath A K, Tsilidis K, Agudo A, Schulze M B, Rothwell J, Cadeau C, Severi S, Weiderpass E, Gunter M J, Dossus L
Abstract excerpt
BACKGROUND: Excess body fatness and hyperinsulinemia are both associated with an increased risk of postmenopausal breast cancer. However, whether women with high body fatness but normal insulin levels or those with normal body fatness and high levels of insulin are at elevated risk of breast cancer is not known. We investigated the associations of metabolically defined body size and shape phenotypes with the risk...
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