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Sensitivity of African swine fever virus to type I interferon is linked to genes within multigene families 360 and 505

1 Apr 2016

Abstract excerpt

African swine fever virus (ASFV) causes a lethal haemorrhagic disease of pigs. There are conflicting reports on the role of interferon in ASFV infection. We therefore analysed the interaction of ASFV with porcine interferon, in vivo and in vitro. Virulent ASFV induced biologically active IFN in the circulation of pigs from day 3-post infection, whereas low virulent OUR T88/3, which lacks genes from multigene...

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PMID: 27043071
DOI: 10.1016/j.virol.2016.03.019

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