Article
Increased Free Circulating DNA Integrity Index as a Serum Biomarker in Patients with Colorectal Carcinoma
11 Apr 2016
Abstract excerpt
BACKGROUND: Cell-free DNA circulating in blood is a candidate biomarker for malignant tumors. Unlike uniformly truncated DNA released from apoptotic non diseased cells, DNA released from necrotic cancer cells varies in size. OBJECTIVES: To measure the DNA integrity index in serum and the absolute DNA concentration to assess their clinical utility as potential serum biomarkers for colorectal carcinoma (CRC)...
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