Article
Circulating free tumor DNA and colorectal cancer.
Gastroenterologie clinique et biologique - 1 Dec 2010
Lecomte T, Ceze N, Dorval E, Laurent-Puig P
Abstract excerpt
Cancer is characterized by multiple somatic genetic and epigenetic alterations that could be useful as molecular markers for detecting tumor DNA in different bodily fluids. In patients with various diseases as well as in healthy subjects, circulating plasma and serum carry small amounts of non-cell-bound DNA. In this free circulating DNA, tumor-associated molecular alterations can be detected in patients who have...
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