Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced self-renewal of human pluripotent stem cells by simulated microgravity

4 Jul 2022

Abstract excerpt

A systematic study on the biological effects of simulated microgravity (sµg) on human pluripotent stem cells (hPSC) is still lacking. Here, we used a fast-rotating 2-D clinostat to investigate the sµg effect on proliferation, self-renewal, and cell cycle regulation of hPSCs. We observed significant upregulation of protein translation of pluripotent transcription factors in hPSC cultured in sµg compared to cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics, Aging, and Longevity in Model Organisms
Share to Pluripotent Stem Cells Research
Share to Spaceflight effects on biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35787634
DOI: 10.1038/s41526-022-00209-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced self-renewal of human pluripotent stem cells by simulated microgravityPMID 35787634Read ↗

Conserved mechanisms of self-renewal and pluripotency in mouse and human ESCs regulated by simulated microgravity using a 3D clinostatSemantic proximity Read ↗

Simulated Microgravity and 3D Culture Enhance Induction, Viability, Proliferation and Differentiation of Cardiac Progenitors from Human Pluripotent Stem CellsSemantic proximity Read ↗

Simulated Microgravity Modulates Differentiation Processes of Embryonic Stem CellsSemantic proximity Read ↗

“Microgravity” as a unique and useful stem cell culture environment for cell-based therapySemantic proximity Read ↗

Real microgravity condition promoted regeneration capacity of induced pluripotent stem cells during the TZ‐1 space missionSemantic proximity Read ↗

Discoveries from human stem cell research in space that are relevant to advancing cellular therapies on EarthSemantic proximity Read ↗

Space microgravity increases expression of genes associated with proliferation and differentiation in human cardiac spheresSemantic proximity Read ↗

Space microgravity improves proliferation of human iPSC-derived cardiomyocytesSemantic proximity Read ↗

Effects of simulated microgravity on the expression profiles of RNA during osteogenic differentiation of human bone marrow mesenchymal stem cellsSemantic proximity Read ↗

Stress Factors as Possible Regulators of Pluripotent Stem Cell Survival and DifferentiationSemantic proximity Read ↗

Microgravity, Stem Cells, and Cancer: A New Hope for Cancer TreatmentSemantic proximity Read ↗

Omics Studies of Specialized Cells and Stem Cells under Microgravity ConditionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.