Article
Ultra-Deep Sequencing of HIV-1 near Full-Length and Partial Proviral Genomes Reveals High Genetic Diversity among Brazilian Blood Donors.
PloS one - 1 Jan 2016
Pessôa Rodrigo, Loureiro Paula, Esther Lopes Maria, Carneiro-Proietti Anna B F, Sabino Ester C, Busch Michael P, Sanabani Sabri S
Abstract excerpt
BACKGROUND: Here, we aimed to gain a comprehensive picture of the HIV-1 diversity in the northeast and southeast part of Brazil. To this end, a high-throughput sequencing-by-synthesis protocol and instrument were used to characterize the near full length (NFLG) and partial HIV-1 proviral genome in 259 HIV-1 infected blood donors at four major blood centers in Brazil: Pro-Sangue foundation (São Paulo state (SP), n...
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