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Article

Multiplexed next-generation sequencing and de novo assembly to obtain near full-length HIV-1 genome from plasma virus.

Journal of virological methods - 1 Oct 2016

Aralaguppe Shambhu G, Siddik Abu Bakar, Manickam Ashokkumar, Ambikan Anoop T, Kumar Milner M, Fernandes Sunjay Jude, Amogne Wondwossen, Bangaruswamy Dhinoth K, Hanna Luke Elizabeth, Sonnerborg Anders, Neogi Ujjwal

Abstract excerpt

Analysing the HIV-1 near full-length genome (HIV-NFLG) facilitates new understanding into the diversity of virus population dynamics at individual or population level. In this study we developed a simple but high-throughput next generation sequencing (NGS) protocol for HIV-NFLG using clinical specimens and validated the method against an external quality control (EQC) panel. Clinical specimens (n=105) were...

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PMID: 27448822
DOI: 10.1016/j.jviromet.2016.07.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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