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Article

Heme sensing in Bacillus thuringiensis: a supplementary HssRS-regulated heme resistance system.

FEMS microbiology letters - 1 May 2016

Schmidt Rachel M, Carter Micaela M, Chu Michelle L, Latario Casey J, Stadler Sarah K, Stauff Devin L

Abstract excerpt

Several Gram-positive pathogens scavenge host-derived heme to satisfy their nutritional iron requirement. However, heme is a toxic molecule capable of damaging the bacterial cell. Gram-positive pathogens within the phylum Firmicutes overcome heme toxicity by sensing heme through HssRS, a two-component system that regulates the heme detoxification transporter HrtAB. Here we show that heme sensing by HssRS and heme...

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Identifiers

PMID: 27030728
DOI: 10.1093/femsle/fnw076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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