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Old and New Glycopeptide Antibiotics: Action and Resistance

4 Nov 2014

Abstract excerpt

Glycopeptides are considered antibiotics of last resort for the treatment of life-threatening infections caused by relevant Gram-positive human pathogens, such as Staphylococcus aureus, Enterococcus spp. and Clostridium difficile. The emergence of glycopeptide-resistant clinical isolates, first among enterococci and then in staphylococci, has prompted research for second generation glycopeptides and a flurry of...

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PMID: 27025757
DOI: 10.3390/antibiotics3040572

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