MicroRNA BIOGENESIS, FUNCTIONALITY AND CANCER RELEVANCE

doi:10.5507/bp.2006.029

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Article

MicroRNA BIOGENESIS, FUNCTIONALITY AND CANCER RELEVANCE

1 Dec 2006

Abstract excerpt

BACKGROUND: MicroRNAs (miRNA) are small non-coding RNAs that negatively regulate gene expression in a sequence- specific manner. Post-transcriptional silencing of target genes by miRNA occurs either by specific cleavage of homologous mRNA or by specific inhibition of protein synthesis. MiRNAs are essential regulators of various processes such as proliferation, differentiation, development, cell death and...

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PMID: 17426780
DOI: 10.5507/bp.2006.029

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