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Morphogenesis of myocardial trabeculae in the mouse embryo

29 Mar 2016

Abstract excerpt

Formation of trabeculae in the embryonic heart and the remodelling that occurs prior to birth is a conspicuous, but poorly understood, feature of vertebrate cardiogenesis. Mutations disrupting trabecular development in the mouse are frequently embryonic lethal, testifying to the importance of the trabeculae, and aberrant trabecular structure is associated with several human cardiac pathologies. Here, trabecular...

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PMID: 27020702
DOI: 10.1111/joa.12465

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