Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Efficient generation of functional hepatocyte-like cells from mouse liver progenitor cells via indirect co-culture with immortalized human hepatic stellate cells.

Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Apr 2016

Pan Xiao-Ping, Wang Yi-Ni, Yu Xiao-Peng, Zhu Chun-Xia, Li Jian-Zhou, Du Wei-Bo, Zhang Yi-Min, Cao Hong-Cui, Zhang Yan-Hong, Zhu Dan-Hua, Yeoh George C, Li Lan-Juan

Abstract excerpt

BACKGROUND: Differentiation of liver progenitor cells (LPCs) to functional hepatocytes holds great potential to develop new strategies for hepatocyte transplantation and the screening of drug-induced cytotoxicity. However, reports on the efficient and convenient hepatic differentiation of LPCs to hepatocytes are few. The present study aims to investigate the possibility of generating functional hepatocytes from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albumins
Share to Culture Media, Conditioned

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1A2

Share to Glycogen

Share to Hepatic Stellate Cells

Share to Lipoproteins, LDL

Share to Paracrine Communication

Source

Identifiers

PMID: 27020634
DOI: 10.1016/s1499-3872(16)60074-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Efficient generation of functional hepatocyte-like cells from mouse liver progenitor cells via indirect co-culture with immortalized human hepatic stellate cells.PMID 27020634Read ↗

An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells.Semantic proximity Read ↗

Pluripotent Stem Cell-Derived Hepatocyte-like Cells: Induction Methods and ApplicationsSemantic proximity Read ↗

Advancements in Disease Modeling and Drug Discovery Using iPSC-Derived Hepatocyte-like CellsSemantic proximity Read ↗

Advances in generating liver cells from pluripotent stem cells as a tool for modeling liver diseasesSemantic proximity Read ↗

Generation of hepatocyte-like cells from human induced pluripotent stem (iPS) cells by co-culturing embryoid body cells with liver non-parenchymal cell line TWNT-1.Semantic proximity Read ↗

Cellular Crosstalk Promotes Hepatic Progenitor Cell Proliferation and Stellate Cell Activation in 3D Co-cultureSemantic proximity Read ↗

Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturationSemantic proximity Read ↗

Generation of Hepatocytes and Nonparenchymal Cell Codifferentiation System from Human-Induced Pluripotent Stem CellsSemantic proximity Read ↗

Generation of liver organoids from human induced pluripotent stem cells as liver fibrosis and steatosis modelsSemantic proximity Read ↗

Hepatic differentiation of liver-derived progenitor cells and their characterization by microRNA analysis.Semantic proximity Read ↗

Different approaches for transformation of mesenchymal stem cells into hepatocyte-like cellsSemantic proximity Read ↗

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.