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Article

Genome Editing of Structural Variations: Modeling and Gene Correction.

Trends in biotechnology - 1 Jul 2016

Park Chul-Yong, Sung Jin Jea, Kim Dong-Wook

Abstract excerpt

The analysis of chromosomal structural variations (SVs), such as inversions and translocations, was made possible by the completion of the human genome project and the development of genome-wide sequencing technologies. SVs contribute to genetic diversity and evolution, although some SVs can cause diseases such as hemophilia A in humans. Genome engineering technology using programmable nucleases (e.g., ZFNs,...

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PMID: 27016031
DOI: 10.1016/j.tibtech.2016.02.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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