Article
A Novel Multifunctional Compound Camellikaempferoside B Decreases Aβ Production, Interferes with Aβ Aggregation, and Prohibits Aβ-Mediated Neurotoxicity and Neuroinflammation.
ACS chemical neuroscience - 20 Apr 2016
Yang Shigao, Liu Wen, Lu Shuai, Tian Yong-zhen, Wang Wei-yun, Ling Tie-jun, Liu Rui-tian
Abstract excerpt
Accumulating evidence suggested that soluble oligomeric β-amyloid protein (Aβ) exerts diverse roles in neuronal cell death, neuroinflammation, oxidative stress, and the eventual dementia associated with Alzheimer's disease (AD). Developing an agent with multiple properties may be a reasonable strategy for the treatment of AD. In this study, we isolated a novel multifunctional compound named camellikaempferoside B...
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