Glutathione S-transferase K1 genotype and overweight status in schizophrenia patients: A pilot study.

doi:10.1016/j.psychres.2016.03.025

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Glutathione S-transferase K1 genotype and overweight status in schizophrenia patients: A pilot study.

Psychiatry research - 30 May 2016

Oniki Kentaro, Kamihashi Ryoko, Tomita Tetsu, Ishioka Masamichi, Yoshimori Yuki, Osaki Natsumi, Tsuchimine Shoko, Sugawara Norio, Kajiwara Ayami, Morita Kazunori, Miyata Keishi, Otake Koji, Nakagawa Kazuko, Ogata Yasuhiro, Saruwatari Junji, Yasui-Furukori Norio

Abstract excerpt

Elevated oxidative stress in mitochondria and mitochondrial dysfunction are associated with weight gain in schizophrenia (SCZ) patients. Glutathione S-transferase kappa 1 (GSTK1) protects cells against exogenous and endogenous oxidative stress in the mitochondria. This exploratory study investigated the possible effects of a common GSTK1 polymorphism (rs1917760, G-1308T) on the risk for overweight status among...

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PMID: 27010189
DOI: 10.1016/j.psychres.2016.03.025

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GSTK1

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