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Article

Decreased level of RASSF6 in sporadic colorectal cancer and its anti-tumor effects both in vitro and in vivo.

Oncotarget - 12 Apr 2016

Chen Erfei, Yang Fangfang, He Hongjuan, Lei Lei, Liu Ruitao, Du Le, Dong Jing, Wang Meng, Yang Jin

Abstract excerpt

Ras-association domain family protein 6 (RASSF6) is a member of tumor suppressor RASSFs family with a wide range of function from RAS interaction, Hippo signaling involvement to cell cycle and apoptosis regulation. RASSF6 is reported inactivated in various types of cancer. However, whether RASSF6 is associated with colorectal cancer and the underlying mechanisms have yet to be investigated. In our previous exome...

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Identifiers

PMID: 27009808
DOI: 10.18632/oncotarget.7852
PMCID: PMC4991420

Genes

RASSF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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