Article
Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Sept 2016
Mooney Michael A, McWeeney Shannon K, Faraone Stephen V, Hinney Anke, Hebebrand Johannes, Nigg Joel T, Wilmot Beth
Abstract excerpt
Despite a wealth of evidence for the role of genetics in attention deficit hyperactivity disorder (ADHD), specific and definitive genetic mechanisms have not been identified. Pathway analyses, a subset of gene-set analyses, extend the knowledge gained from genome-wide association studies (GWAS) by providing functional context for genetic associations. However, there are numerous methods for association testing of...
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