Article
Discovery of unfixed endogenous retrovirus insertions in diverse human populations.
Proceedings of the National Academy of Sciences of the United States of America - 19 Apr 2016
Wildschutte Julia Halo, Williams Zachary H, Montesion Meagan, Subramanian Ravi P, Kidd Jeffrey M, Coffin John M
Abstract excerpt
Endogenous retroviruses (ERVs) have contributed to more than 8% of the human genome. The majority of these elements lack function due to accumulated mutations or internal recombination resulting in a solitary (solo) LTR, although members of one group of human ERVs (HERVs), HERV-K, were recently active with members that remain nearly intact, a subset of which is present as insertionally polymorphic loci that...
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