Article
Analyzing Deoxyribose Nucleic Acid from Malaria Rapid Diagnostic Tests to Study Plasmodium falciparum Genetic Diversity in Mali.
The American journal of tropical medicine and hygiene - 1 Jun 2016
Nabet Cécile, Doumbo Safiatou, Jeddi Fakhri, Sagara Issaka, Manciulli Tommaso, Tapily Amadou, L'Ollivier Coralie, Djimde Abdoulaye, Doumbo Ogobara K, Piarroux Renaud
Abstract excerpt
We evaluated the use of positive malaria rapid diagnostic tests (mRDTs) to determine genetic diversity of Plasmodium falciparum in Mali. Genetic diversity was assessed via multiple loci variable number of tandem repeats analysis (MLVA). We performed DNA extraction from 104 positive and 30 negative used mRDTs that had been stored at ambient temperature for up to 14 months. Extracted DNA was analyzed via...
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