Article
DNA recovery from used malaria RDT to detect Plasmodium species and to assess Plasmodium falciparum genetic diversity: a pilot study in Madagascar.
Malaria journal - 26 Jul 2022
Andrianaranjaka Voahangy Hanitriniaina I, Ravaoarisoa Elisabeth, Rakotomanga Tovonahary A, Ralinoro Fanomezantsoa, Rakoto Danielle A Doll, Randrianarivo Ranjàna H, Jeannoda Victor, Ratsimbasoa Arsène
Abstract excerpt
BACKGROUND: Rapid diagnostic tests (RDT) are widely used for malaria diagnosis in Madagascar, where Plasmodium falciparum is the predominant species. Molecular diagnosis is essential for malaria surveillance, but requires additional blood samples for DNA extraction. Used RDTs is an attractive alternative that can be used as a source of DNA. Plasmodium falciparum genetic diversity and multiplicity of infection,...
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