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Article

Mechanisms of resistance to insecticides targeting RDL GABA receptors in planthoppers.

Neurotoxicology - 1 May 2017

Nakao Toshifumi

Abstract excerpt

Lindane and cyclodienes, such as dieldrin and α-endosulfan, represent the first generation of noncompetitive antagonists (NCAs) against the insect RDL GABA receptor. It has been reported that A2'S and A2'G mutations in the membrane-spanning region M2 of the RDL GABA receptor confer resistance to lindane and cyclodienes. Fipronil is a second-generation NCA, but A2'S and A2'G mutations provide a low level of...

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Identifiers

PMID: 27000517
DOI: 10.1016/j.neuro.2016.03.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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