Article
Q787Q EGFR Polymorphism as a Prognostic Factor for Lung Squamous Cell Carcinoma.
Oncology - 1 Jan 2016
Koh Young Wha, Kim Han Jo, Kwon Hyog Young, Han Jae-Ho, Lee Chi-Kyou, Lee Moon-Su, Kim Chang-Jin, Baek Moo-Jun, Jeong Dongjun
Abstract excerpt
OBJECTIVE: EGFR genetic polymorphisms have been investigated for carcinogenesis in various tumors including lung cancer. We evaluated EGFR mutations in four exons, with an emphasis on the Q787Q EGFR polymorphism in non-small-cell lung cancer. METHODS: To determine the presence of the Q787Q polymorphism in patients with lung cancer, we performed direct sequencing analyses of four exons for 83 squamous cell...
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