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Article

Human Embryonic Stem Cell Lines with Lesions in FOXP3 and NF1.

PloS one - 1 Jan 2016

Zhu Hui, Behr Barry, Reddy Vikrant V, Hughes Mark, Pan Yuqiong, Baker Julie

Abstract excerpt

Human embryonic stem cells (hESCs) are derived from the inner cell mass (ICM) of blastocyst staged embryos. Spare blastocyst staged embryos were obtained by in vitro fertilization (IVF) and donated for research purposes. hESCs carrying specific mutations can be used as a powerful cell system in modeling human genetic disorders. We obtained preimplantation genetic diagnosed (PGD) blastocyst staged embryos with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26990425
DOI: 10.1371/journal.pone.0151836
PMCID: PMC4798423

Genes

FOXP3
PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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