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Article

Generation of an induced pluripotent stem cell line from a type 1 neurofibromatosis patient with NF1 mutation.

Stem cell research - 1 Dec 2024

Xin Hongmei, Li Yixiao, Zhang Kaihui, Ji Aihua, Fan Meili

Abstract excerpt

A human induced pluripotent stem cell (iPSC) line was generated from patient with type 1 neurofibromatosis (NF-1), carrying heterozygous mutation in NF1 gene. Peripheral blood mononuclear cells (PBMCs) were reprogrammed using non-integrating delivery of KFL4, OCT4, SOX2, BCL-XL and c-MYC. The iPSC line expresses pluripotency markers, displays a normal karyotype, and is able to differentiate into three germ layers...

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Identifiers

PMID: 39332134
DOI: 10.1016/j.scr.2024.103568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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