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Article

Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system.

International journal of molecular sciences - 30 Sept 2013

Horii Takuro, Tamura Daiki, Morita Sumiyo, Kimura Mika, Hatada Izuho

Abstract excerpt

Genome manipulation of human induced pluripotent stem (iPS) cells is essential to achieve their full potential as tools for regenerative medicine. To date, however, gene targeting in human pluripotent stem cells (hPSCs) has proven to be extremely difficult. Recently, an efficient genome manipulation technology using the RNA-guided DNase Cas9, the clustered regularly interspaced short palindromic repeats (CRISPR)...

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Identifiers

PMID: 24084724
DOI: 10.3390/ijms141019774
PMCID: PMC3821585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system.PMID 24084724Read ↗

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