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Article

Meta-analysis of the serotonin transporter promoter variant (5-HTTLPR) in relation to adverse environment and antisocial behavior.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2016

Tielbeek Jorim J, Karlsson Linnér Richard, Beers Koko, Posthuma Danielle, Popma Arne, Polderman Tinca J C

Abstract excerpt

Several studies have suggested an association between antisocial, aggressive, and delinquent behavior and the short variant of the serotonin transporter gene polymorphism (5-HTTLPR). Yet, genome wide and candidate gene studies in humans have not convincingly shown an association between these beh...

Topics

Aggression
Alleles
Antisocial Personality Disorder
Environment
Female
Gene-Environment Interaction
Genotype
Humans
Male
Polymorphism, Genetic
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Factors

Serotonin Plasma Membrane Transport Proteins

Social Behavior

Source

Identifiers

PMID: 26990155
DOI: 10.1002/ajmg.b.32442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-26990155-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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