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Article

GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer

18 Mar 2016

Abstract excerpt

BACKGROUND: GLI pathogenesis-related 1 (GLIPR1) was originally identified in glioblastomas and its expression was also found to be down-regulated in prostate cancer. Functional studies revealed both growth suppression and proapoptotic activities for GLIPR1 in multiple cancer cell lines. GLIPR1's role in lung cancer has not been investigated. Protein arginine methyltransferase 5 (PRMT5) is a protein arginine...

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PMID: 26988096
DOI: 10.1186/s12943-016-0508-4

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