Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor-Free Transplantation of Patient-Derived Induced Pluripotent Stem Cell Progeny for Customized Islet Regeneration.

Stem cells translational medicine - 1 May 2016

El Khatib Moustafa M, Ohmine Seiga, Jacobus Egon J, Tonne Jason M, Morsy Salma G, Holditch Sara J, Schreiber Claire A, Uetsuka Koji, Fusaki Noemi, Wigle Dennis A, Terzic Andre, Kudva Yogish C, Ikeda Yasuhiro

Abstract excerpt

UNLABELLED: Human induced pluripotent stem cells (iPSCs) and derived progeny provide invaluable regenerative platforms, yet their clinical translation has been compromised by their biosafety concern. Here, we assessed the safety of transplanting patient-derived iPSC-generated pancreatic endoderm/progenitor cells. Transplantation of progenitors from iPSCs reprogrammed by lentiviral vectors (LV-iPSCs) led to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Heterografts
Share to Islets of Langerhans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Islets of Langerhans Transplantation

Share to Keratinocytes

Share to Lentivirus

Share to Mice, SCID

Share to Proto-Oncogene Proteins c-myc

Share to Regeneration

Source

Open in PubMed Open full text

Identifiers

PMID: 26987352
DOI: 10.5966/sctm.2015-0017
PMCID: PMC4835241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor-Free Transplantation of Patient-Derived Induced Pluripotent Stem Cell Progeny for Customized Islet Regeneration.PMID 26987352Read ↗

Strategies to Improve the Safety of iPSC-Derived β Cells for β Cell Replacement in DiabetesSemantic proximity Read ↗

Transgene-Free Disease-Specific Induced Pluripotent Stem Cells from Patients with Type 1 and Type 2 DiabetesSemantic proximity Read ↗

Potential of Induced Pluripotent Stem Cells for Use in Gene Therapy: History, Molecular Bases, and Medical PerspectivesSemantic proximity Read ↗

Tumorigenicity risk of iPSCs <i>in vivo</i>: nip it in the budSemantic proximity Read ↗

Engineered T cells from induced pluripotent stem cells: from research towards clinical implementationSemantic proximity Read ↗

A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapySemantic proximity Read ↗

The Current Status of Allogenic Islet Cell TransplantationSemantic proximity Read ↗

The prospect of induced pluripotent stem cells for diabetes mellitus treatmentSemantic proximity Read ↗

Preventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders.Semantic proximity Read ↗

Generation of clinically relevant "induced pluripotent stem" (iPS) cells.Semantic proximity Read ↗

Potential of mesenchymal stromal cells for improving islet transplantation outcomes.Semantic proximity Read ↗

Development of an inducible caspase-9 safety switch for pluripotent stem cell–based therapiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.