Article
Potential of mesenchymal stromal cells for improving islet transplantation outcomes.
Current opinion in pharmacology - 1 Dec 2018
Rackham Chloe L, Jones Peter M
Abstract excerpt
Allogeneic islet transplantation as a therapy for Type 1 Diabetes (T1D) is restricted by the limited availability of donor islets, loss of functional islets during pre-transplantation culture in vitro and further extensive loss during the immediate post-transplantation period when islet function and survival is compromised by the hypoxic, inflammatory host environment. In the longer term pathogenic T cell...
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