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Article

Cooperation between distinct viral variants promotes growth of H3N2 influenza in cell culture.

eLife - 15 Mar 2016

Xue Katherine S, Hooper Kathryn A, Ollodart Anja R, Dingens Adam S, Bloom Jesse D

Abstract excerpt

RNA viruses rapidly diversify into quasispecies of related genotypes. This genetic diversity has long been known to facilitate adaptation, but recent studies have suggested that cooperation between variants might also increase population fitness. Here, we demonstrate strong cooperation between two H3N2 influenza variants that differ by a single mutation at residue 151 in neuraminidase, which normally mediates...

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Identifiers

PMID: 26978794
DOI: 10.7554/eLife.13974
PMCID: PMC4805539

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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