Article
Development of a control region-based mtDNA SNaPshot™ selection tool, integrated into a mini amplicon sequencing method.
Science & justice : journal of the Forensic Science Society - 1 Mar 2016
Weiler Natalie E C, de Vries Gerda, Sijen Titia
Abstract excerpt
Mitochondrial DNA (mtDNA) analysis is regularly applied to forensic DNA samples with limited amounts of nuclear DNA (nDNA), such as hair shafts and bones. Generally, this mtDNA analysis involves examination of the hypervariable control region by Sanger sequencing of amplified products. When samples are severely degraded, small-sized amplicons can be applied and an earlier described mini-mtDNA method by Eichmann...
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