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Article

Seeking Optimal Region-Of-Interest (ROI) Single-Value Summary Measures for fMRI Studies in Imaging Genetics.

PloS one - 1 Jan 2016

Tong Yunxia, Chen Qiang, Nichols Thomas E, Rasetti Roberta, Callicott Joseph H, Berman Karen F, Weinberger Daniel R, Mattay Venkata S

Abstract excerpt

A data-driven hypothesis-free genome-wide association (GWA) approach in imaging genetics studies allows screening the entire genome to discover novel genes that modulate brain structure, chemistry, and function. However, a whole brain voxel-wise analysis approach in such genome-wide based imaging genetic studies can be computationally intense and also likely has low statistical power since a stringent multiple...

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PMID: 26974435
DOI: 10.1371/journal.pone.0151391
PMCID: PMC4790904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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