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Article

Coexistence of EGFR T790M mutation and common activating mutations in pretreatment non-small cell lung cancer: A systematic review and meta-analysis.

Lung cancer (Amsterdam, Netherlands) - 1 Apr 2016

Chen Li-Yang, Molina-Vila Miguel A, Ruan Sheng-Yuan, Su Kang-Yi, Liao Wei-Yu, Yu Kai-Lun, Ho Chao-Chi, Shih Jin-Yuan, Yu Chong-Jen, Yang James Chih-Hsin, Rosell Rafael, Yang Pan-Chyr

Abstract excerpt

OBJECTIVE: Previous studies have indicated that EGFR exon 19 deletions in non-small cell lung cancer (NSCLC) are associated with better outcomes to tyrosine kinase inhibitors (TKIs) than the L858R mutation. This study aimed to evaluate whether T790M, a resistant mutation, is more likely to coexist with L858R mutation than with exon 19 deletions in pretreatment NSCLC patients. MATERIALS AND METHOD: We searched...

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Identifiers

PMID: 26973206
DOI: 10.1016/j.lungcan.2016.01.019

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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