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Article

Co-occurring genetic alterations and primary EGFR T790M mutations detected by NGS in pre-TKI-treated NSCLCs.

Journal of cancer research and clinical oncology - 1 Feb 2020

Tang Yuan, Che Nanying, Yu Yang, Gao Yun, Shi Huaiyin, Feng Qin, Wei Bing, Ma Liheng, Gao Min, Ma Jie, Lin Dongmei

Abstract excerpt

INTRODUCTION: Next-generation sequencing (NGS)-based assays to understand various mutations and co-occurrence of genomic alterations in non-small cell lung cancer (NSCLC) have enabled understanding of treatment impact on clinical outcomes. METHODS: This retrospective study was conducted in 1353 formalin-fixed paraffin-embedded (FFPE) tissues from surgically resected, pre-TKI-treated NSCLC patients with identified...

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Identifiers

PMID: 31696302
DOI: 10.1007/s00432-019-03065-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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