Article
[Pathophysiology of eosinophilic granulomatosis with polyangitis (Churg-Strauss)].
La Revue de medecine interne - 1 May 2016
Chaigne B, Dion J, Guillevin L, Mouthon L, Terrier B
Abstract excerpt
Eosinophilic granulomatosis with polyangitis (EGPA) (formerly Churg-Strauss syndrome) is a rare small-sized vessel vasculitis belonging to the group of anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitides. MPO-ANCA is present in only 31 to 38% of patients. In this review, we describe the pathophysiology of EGPA, which is characterized by a genetic predisposition, an environmental association, and a...
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