Article
In vitro activity of tedizolid against linezolid-resistant staphylococci and enterococci.
Diagnostic microbiology and infectious disease - 1 May 2016
Silva-Del Toro Stephanie L, Greenwood-Quaintance Kerryl E, Patel Robin
Abstract excerpt
The tedizolid MIC of 27 clinical isolates of linezolid-resistant staphylococci and enterococci was determined. Tedizolid MICs were ≥1μg/mL and were 4- to 32-fold lower than those of linezolid. Linezolid resistance mechanisms included G2576T 23S rRNA gene and rplC and rplD mutations.
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