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Article

Interactions between CYP2E1, GSTZ1 and GSTT1 polymorphisms and exposure to drinking water trihalomethanes and their association with semen quality.

Environmental research - 1 May 2016

Yang Pan, Zeng Qiang, Cao Wen-Cheng, Wang Yi-Xin, Huang Zhen, Li Jin, Liu Chong, Lu Wen-Qing

Abstract excerpt

Trihalomethanes (THMs) have been reported to be associated with altered semen quality, and this association may be modified by inherited differences in cytochrome P450 (CYP2E1) and glutathione S-transferase (GSTZ1 and GSTT1), which metabolize THMs. We conducted a cross-sectional study to examine the interactions between CYP2E1, GSTZ1 and GSTT1 polymorphisms and exposure to THMs on semen quality among 401 men from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26970898
DOI: 10.1016/j.envres.2016.03.009

Genes

GSTT1
GSTZ1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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