Article
Association of GSTM1 and GSTT1 gene polymorphisms and in-vitro fertilisation outcome in a population in northern Iran.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology - 1 Jan 2015
Karimlo F K, Mashayekhi F, Sorouri Z Z, Bahador M H, Salehi Z
Abstract excerpt
Implantation failure is a major limiting step for in-vitro fertilisation (IVF). Embryo implantation is the result of the interaction of the embryo with the endometrium. Oxidative stress (OS) can cause defective embryo development and retardation. Genetic polymorphisms of detoxicating enzymes, such as glutathione S-transferases (GSTs), may play an important role in the outcome of embryo implantation. GSTM1 and...
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