Article
Negative effects of serum p,p'-DDE on sperm parameters and modification by genetic polymorphisms.
Environmental research - 1 May 2009
Messaros Bridget M, Rossano Mary G, Liu Guanghui, Diamond Michael P, Friderici Karen, Nummy-Jernigan Katherine, Daly Douglas, Puscheck Elizabeth, Paneth Nigel, Wirth Julia J
Abstract excerpt
OBJECTIVE: Effects of ambient exposure to DDT and its metabolites (DDE-DDT) on human sperm parameters and the role of genetic polymorphisms in modifying the association were investigated. METHODS: Demographics, medical history data, blood and semen samples were obtained from the first 336 male partners of couples presenting to 2 infertility clinics. Serum was analyzed for organochlorines (OC) and DNA for...
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